Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality

Neutrophils generated by granulocyte colony‐stimulating factor (GCSF) are functionally immature and, consequently, cannot effectively reduce infection and infection‐related mortality in cancer chemotherapy‐induced neutropenia (CCIN). Am80, a retinoic acid (RA) agonist that enhances granulocytic diff...

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Publicat a:EMBO Mol Med
Autors principals: Li, Lin, Qi, Xiaotian, Sun, Weili, Abdel‐Azim, Hisham, Lou, Siyue, Zhu, Hong, Prasadarao, Nemani V, Zhou, Alice, Shimada, Hiroyuki, Shudo, Koichi, Kim, Yong‐Mi, Khazal, Sajad, He, Qiaojun, Warburton, David, Wu, Lingtao
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090663/
https://ncbi.nlm.nih.gov/pubmed/27737899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606434
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