Synthetic Retinoid AM80 Inhibits Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis

Recent evidence suggests that interleukin-17-producing CD4(+) T cells (Th17 cells) are the dominant pathogenic cellular component in autoimmune inflammatory diseases, including multiple sclerosis. It has recently been demonstrated that all-trans retinoic acid can suppress Th17 differentiation and pr...

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Autors principals: Klemann, Christian, Raveney, Benjamin J.E., Klemann, Anna K., Ozawa, Tomoko, von Hörsten, Stephan, Shudo, Koichi, Oki, Shinji, Yamamura, Takashi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684188/
https://ncbi.nlm.nih.gov/pubmed/19389933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081084
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