The transcription factors STAT5A/B regulate GM-CSF–mediated granulopoiesis

Neutrophils play a vital role in the immune defense, which is evident by the severity of neutropenia causing life-threatening infections. Granulocyte macrophage-colony stimulating factor (GM-CSF) controls homeostatic and emergency development of granulocytes. However, little is known about the contr...

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Autori principali: Kimura, Akiko, Rieger, Michael A., Simone, James M., Chen, Weiping, Wickre, Mark C., Zhu, Bing-Mei, Hoppe, Philipp S., O'Shea, John J., Schroeder, Timm, Hennighausen, Lothar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Phagocytes, Granulocytes, and Myelopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780307/
https://ncbi.nlm.nih.gov/pubmed/19779039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-216390
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