Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice

The majority of peripheral serotonin is stored in platelets, which secrete it on activation. Serotonin releases Weibel-Palade bodies (WPBs) and we asked whether absence of platelet serotonin affects neutrophil recruitment in inflammatory responses. Tryptophan hydroxylase (Tph)1–deficient mice, lacki...

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Détails bibliographiques
Auteurs principaux: Duerschmied, Daniel, Suidan, Georgette L., Demers, Melanie, Herr, Nadine, Carbo, Carla, Brill, Alexander, Cifuni, Stephen M., Mauler, Maximilian, Cicko, Sanja, Bader, Michael, Idzko, Marco, Bode, Christoph, Wagner, Denisa D.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Phagocytes, Granulocytes, and Myelopoiesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567335/
https://ncbi.nlm.nih.gov/pubmed/23243271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-437392
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