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Inactivation of Met471Cys Tyramine β-Monooxygenase Results from Site-Specific Cysteic Acid Formation()
Tyramine β-monooxygenase (TβM), the insect homologue of dopamine β-monooxygenase, is a neuroregulatory enzyme that catalyzes the beta hydroxylation of tyramine to yield octopamine. Mutation of the methionine (Met) ligand to Cu(M) of TβM, Met471Cys, yielded a form of TβM that is catalytically active...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567250/ https://ncbi.nlm.nih.gov/pubmed/22891760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300456f |
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