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Identification of Thermal Conduits that Link the Protein-Water Interface to the Active Site Loop and Catalytic Base in Enolase
We report here on the salient role of protein mobility in accessing conformational landscapes that enable efficient enzyme catalysis. We are focused on yeast enolase, a highly conserved lyase with a TIM barrel domain and catalytic loop, as part of a larger study of an expected correlation of protein...
में बचाया:
| में प्रकाशित: | J Am Chem Soc |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2021
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7908892/ https://ncbi.nlm.nih.gov/pubmed/33395523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09423 |
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