Fine Mapping of Xq28: Both MECP2 and IRAK1 Contribute to Risk for Systemic Lupus Erythematosus in Multiple Ancestral Groups

OBJECTIVES: The Xq28 region containing IRAK1 and MECP2 has been identified as a risk locus for systemic lupus erythematosus (SLE) in previous genetic association studies. However, due to the strong linkage disequilibrium between IRAK1 and MECP2, it remains unclear which gene is affected by the under...

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主要な著者: Kaufman, Kenneth M., Zhao, Jian, Kelly, Jennifer A., Hughes, Travis, Adler, Adam, Sanchez, Elena, Ojwang, Joshua O., Langefeld, Carl D., Ziegler, Julie T., Williams, Adrienne H., Comeau, Mary E., Marion, Miranda C., Glenn, Stuart B., Cantor, Rita M., Grossman, Jennifer M., Hahn, Bevra H., Song, Yeong Wook, Yu, Chack-Yung, James, Judith A., Guthridge, Joel M., Brown, Elizabeth E., Alarcón, Graciela S., Kimberly, Robert P., Edberg, Jeffrey C., Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Anaya, Juan-Manuel, Boackle, Susan A., Stevens, Anne M., Freedman, Barry I., Criswell, Lindsey A., Pons-Estel, Bernardo A., Lee, Joo-Hyun, Lee, Ji-Seon, Chang, Deh-Ming, Scofield, R Hal, Gilkeson, Gary S., Merrill, Joan T., Niewold, Timothy B., Vyse, Timothy J., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Jacob, Chaim O., Sivils, Kathy Moser, Gaffney, Patrick M., Harley, John B., Sawalha, Amr H., Tsao, Betty P.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567234/
https://ncbi.nlm.nih.gov/pubmed/22904263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-201851
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