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Angiogenin in Parkinson Disease Models: Role of Akt Phosphorylation and Evaluation of AAV-Mediated Angiogenin Expression in MPTP Treated Mice

The angiogenic factor, angiogenin, has been recently linked to both Amyotrophic Lateral Sclerosis (ALS) and Parkinson Disease (PD). We have recently shown that endogenous angiogenin levels are dramatically reduced in an alpha-synuclein mouse model of PD and that exogenous angiogenin protects against...

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Detalhes bibliográficos
Main Authors: Steidinger, Trent U., Slone, Sunny R., Ding, Huiping, Standaert, David G., Yacoubian, Talene A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567051/
https://ncbi.nlm.nih.gov/pubmed/23409128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056092
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