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Angiogenin in Parkinson Disease Models: Role of Akt Phosphorylation and Evaluation of AAV-Mediated Angiogenin Expression in MPTP Treated Mice

The angiogenic factor, angiogenin, has been recently linked to both Amyotrophic Lateral Sclerosis (ALS) and Parkinson Disease (PD). We have recently shown that endogenous angiogenin levels are dramatically reduced in an alpha-synuclein mouse model of PD and that exogenous angiogenin protects against...

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Détails bibliographiques
Auteurs principaux: Steidinger, Trent U., Slone, Sunny R., Ding, Huiping, Standaert, David G., Yacoubian, Talene A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567051/
https://ncbi.nlm.nih.gov/pubmed/23409128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056092
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