Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations

BACKGROUND: There are no reliable markers of malignancy in phaeochromocytomas (PCC) and paragangliomas (PGL). We investigated the relevance of the mammalian target of rapamycin (mTOR)/AKT and hypoxic pathways as novel immunohistochemical markers of malignancy. METHODS: Tissue microarray blocks were...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pinato, D J, Ramachandran, R, Toussi, S T K, Vergine, M, Ngo, N, Sharma, R, Lloyd, T, Meeran, K, Palazzo, F, Martin, N, Khoo, B, Dina, R, Tan, T M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566818/
https://ncbi.nlm.nih.gov/pubmed/23257898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.538
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados