Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behavior

The hypoxic response underlies the pathogenesis and malignant behavior of PCC/PGL. Regulation of PD-1 receptor-ligand signaling, a therapeutically actionable driver of the anti-tumor immune response, is a hypoxic-driven trait across malignancies. We evaluated the prognostic role of PD ligands in ass...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Pinato, David J., Black, James R., Trousil, Sebastian, Dina, Roberto E., Trivedi, Pritesh, Mauri, Francesco A., Sharma, Rohini
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674959/
https://ncbi.nlm.nih.gov/pubmed/29147618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1358332
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