Evidence of functional cross talk between the Notch and NF-κB pathways in nonneoplastic hyperproliferating colonic epithelium

The Notch and NF-κB signaling pathways regulate stem cell function and inflammation in the gut, respectively. We investigate whether a functional cross talk exists between the two pathways during transmissible murine colonic hyperplasia (TMCH) caused by Citrobacter rodentium (CR). During TMCH, NF-κB...

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Hlavní autoři: Ahmed, Ishfaq, Roy, Badal, Chandrakesan, Parthasarathy, Venugopal, Anand, Xia, Lijun, Jensen, Roy, Anant, Shrikant, Umar, Shahid
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Inflammation/Immunity/Mediators
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566617/
https://ncbi.nlm.nih.gov/pubmed/23203159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00372.2012
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