Distinct Compartmentalization of NF-κB Activity in Crypt and Crypt-Denuded Lamina Propria Precedes and Accompanies Hyperplasia and/or Colitis following Bacterial Infection

Citrobacter rodentium induces transmissible murine colonic hyperplasia (TMCH) and variable degrees of inflammation and necrosis depending upon the genetic background. Utilizing C. rodentium-induced TMCH in C3H/HeNHsd inbred mice, we observed significant crypt hyperplasia on days 3 and 7 preceding ac...

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Detalhes bibliográficos
Main Authors: Chandrakesan, Parthasarathy, Ahmed, Ishfaq, Chinthalapally, Anisha, Singh, Pomila, Awasthi, Shanjana, Anant, Shrikant, Umar, Shahid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264290/
https://ncbi.nlm.nih.gov/pubmed/22144489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06101-11
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