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Age sensitizes the kidney to heme protein-induced acute kidney injury
Age increases the risk for ischemic acute kidney injury (AKI). We questioned whether a similar age-dependent injury occurs following exposure to hemoglobin, a known nephrotoxin. Old mice (∼16 mo old), but not young mice (∼6 mo old), when administered hemoglobin, exhibited marked elevation in blood u...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566520/ https://ncbi.nlm.nih.gov/pubmed/23195679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00606.2012 |
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