A phase II study of sirolimus, tacrolimus, and rabbit anti-thymocyte globulin as graft-versus-host prophylaxis after unrelated-donor peripheral blood stem cell transplant

We report on a prospective phase II trial of 32 patients who underwent unrelated donor hematopoietic cell transplantation, with a tacrolimus, sirolimus and rabbit anti-thymoctye globulin GVHD prophylactic regimen. The primary study endpoint was incidence of grades II-IV acute GVHD, with 80% power to...

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Bibliographic Details
Main Authors: Khaled, Samer K., Palmer, Joycelynne, StillerMS, Tracey, Senitzer, David, Maegawa, Rodrigo, Rodriguez, Roberto, Parker, Pablo M., Nademanee, Auayporn, Cai, Ji-Lian, Snyder, David S., Karanes, Chatchada, Osorio, Edna, Thomas, Sandra H., Forman, Stephen J., Nakamura, Ryotaro
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566319/
https://ncbi.nlm.nih.gov/pubmed/23000644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2012.175
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