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Protective Effect of HLA-DPB1 Mismatch Remains Valid in Reduced-Intensity Conditioning Unrelated Donor Hematopoietic Cell Transplantation

A mismatch at HLA-DPB1 locus is associated with higher acute GVHD and lower relapse rate after myeloablative (MAC) allogeneic hematopoietic cell transplantation (alloHCT). Also, in MAC setting, mismatch permissiveness and expression level impact alloHCT outcomes. However, in reduced intensity (RIC),...

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Detalhes bibliográficos
Publicado no:Bone Marrow Transplant
Main Authors: Malki, Monzr M. Al, Gendzekhadze, Ketevan, Stiller, Tracey, Mokhtari, Sally, Karanes, Chatchada, Parker, Pablo, Snyder, David, Forman, Stephen J., Nakamura, Ryotaro, Nademanee, Auayporn
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002238/
https://ncbi.nlm.nih.gov/pubmed/31551519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41409-019-0694-y
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