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TLR2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation
Innate immune signaling associated with Toll like receptors (TLRs) is a key pathway involved in the progression of nonalcoholic steatohepatitis (NASH). Here we show that both TLR2 and palmitic acid are required for activation of the inflammasome, IL-1α and IL-1β, resulting in the progression of NASH...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566276/ https://ncbi.nlm.nih.gov/pubmed/22987396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26081 |
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