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Enantioselective Formal Aza-Diels–Alder Reactions of Enones with Cyclic Imines Catalyzed by Primary Aminothioureas

A highly enantio- and diastereoselective synthesis of indolo- and benzoquinolizidine compounds has been developed through the formal aza-Diels–Alder reaction of enones with cyclic imines. This transformation is catalyzed by a new bifunctional primary aminothiourea that achieves simultaneous activati...

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Detalhes bibliográficos
Main Authors: Lalonde, Mathieu P., McGowan, Meredeth A., Rajapaksa, Naomi S., Jacobsen, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566267/
https://ncbi.nlm.nih.gov/pubmed/23321009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja310718f
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