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Activation of WIP1 Phosphatase by HTLV-1 Tax Mitigates the Cellular Response to DNA Damage

Genomic instability stemming from dysregulation of cell cycle checkpoints and DNA damage response (DDR) is a common feature of many cancers. The cancer adult T cell leukemia (ATL) can occur in individuals infected with human T cell leukemia virus type 1 (HTLV-1), and ATL cells contain extensive chro...

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Autors principals: Dayaram, Tajhal, Lemoine, Francene J., Donehower, Lawrence A., Marriott, Susan J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566092/
https://ncbi.nlm.nih.gov/pubmed/23405243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055989
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