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The HTLV-1 Tax Oncoprotein Represses Ku80 Gene Expression

The HTLV-I oncoprotein Tax interferes with DNA double strand break repair. Since non-homologous end joining (NHEJ) is a major pathway used to repair DNA double strand breaks we examined the effect of Tax on this pathway, with particular interest in the expression and function of Ku80, a critical com...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ducu, Razvan I., Dayaram, Tajhal, Marriott, Susan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112475/
https://ncbi.nlm.nih.gov/pubmed/21571351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.04.012
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