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Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells

The role of cyclin B1 in the clinical therapeutic sensitivity of human esophageal squamous cell carcinoma (ESCC) remains to be defined. In this study, we found that elevated cyclin B1 expression attenuated the apoptosis induced by cisplatin or paclitaxel, while knockdown of cyclin B1 enhanced cispla...

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Bibliografiske detaljer
Main Authors: Ou, Yunwei, Ma, Liying, Ma, Ling, Huang, Zhen, Zhou, Wei, Zhao, Chunling, Zhang, Bailin, Song, Yongmei, Yu, Chunjiang, Zhan, Qimin
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566051/
https://ncbi.nlm.nih.gov/pubmed/23114644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22627
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