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SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT

Secreted protein acidic and rich in cysteine (SPARC) is also known as BM-40 or Osteonectin, a multi-functional protein modulating cell–cell and cell–matrix interactions. In cancer, SPARC is not only linked with a highly aggressive phenotype, but it also acts as a tumor suppressor. In the present stu...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhoopathi, Praveen, Gorantla, Bharathi, Sailaja, G. S., Gondi, Christopher S., Gujrati, Meena, Klopfenstein, Jeffrey D., Rao, Jasti S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342296/
https://ncbi.nlm.nih.gov/pubmed/22567126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036093
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