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Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells

The role of cyclin B1 in the clinical therapeutic sensitivity of human esophageal squamous cell carcinoma (ESCC) remains to be defined. In this study, we found that elevated cyclin B1 expression attenuated the apoptosis induced by cisplatin or paclitaxel, while knockdown of cyclin B1 enhanced cispla...

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Autori principali: Ou, Yunwei, Ma, Liying, Ma, Ling, Huang, Zhen, Zhou, Wei, Zhao, Chunling, Zhang, Bailin, Song, Yongmei, Yu, Chunjiang, Zhan, Qimin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566051/
https://ncbi.nlm.nih.gov/pubmed/23114644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22627
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