Zfp148 Deficiency Causes Lung Maturation Defects and Lethality in Newborn Mice That Are Rescued by Deletion of p53 or Antioxidant Treatment

The transcription factor Zfp148 (Zbp-89, BFCOL, BERF1, htβ) interacts physically with the tumor suppressor p53 and is implicated in cell cycle control, but the physiological role of Zfp148 remains unknown. Here we show that Zfp148 deficiency leads to respiratory distress and lethality in newborn mic...

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Autores principales: Sayin, Volkan I., Nilton, Anna, Ibrahim, Mohamed X., Ågren, Pia, Larsson, Erik, Petit, Marleen M., Hultén, Lillemor Mattsson, Ståhlman, Marcus, Johansson, Bengt R., Bergo, Martin O., Lindahl, Per
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566028/
https://ncbi.nlm.nih.gov/pubmed/23405202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055720
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