The Detergent-Soluble Cytoplasmic Pool of Survivin Suppresses Anoikis and Its Expression Is Associated with Metastatic Disease of Human Colon Cancer

Survivin is a component of the chromosomal passenger complex (CPC) that is essential for accurate chromosome segregation. Interfering with the function of Survivin in mitosis leads to chromosome segregation errors and defective cytokinesis. Survivin contains a Baculovirus IAP Repeat (BIR) and theref...

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Main Authors: Hori, Masato, Miki, Tomoharu, Okamoto, Mayumi, Yazama, Futoshi, Konishi, Hiroaki, Kaneko, Hiroshi, Shimamoto, Fumio, Ota, Takahide, Temme, Achim, Tatsuka, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565976/
https://ncbi.nlm.nih.gov/pubmed/23405201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055710
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