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Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs

BACKGROUND: Rho GTPases function as molecular switches in many different signaling pathways and control a wide range of cellular processes. Rho GDP-dissociation inhibitors (RhoGDIs) regulate Rho GTPase signaling and can function as both negative and positive regulators. The role of RhoGDIs as negati...

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發表在:BMC Syst Biol
Main Authors: Ota, Takahide, Maeda, Masayo, Okamoto, Mayumi, Tatsuka, Masaaki
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312443/
https://ncbi.nlm.nih.gov/pubmed/25628036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0143-5
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