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Apoptosis-independent cleavage of RhoGDIβ at Asp19 during PMA-stimulated differentiation of THP-1 cells to macrophages
Rho GDP-dissociation inhibitor β (RhoGDIβ), a regulator of the Rho family of proteins, is expressed abundantly in the hematopoietic cell lineage. During apoptosis of hematopoietic cells, RhoGDIβ is cleaved by caspase-3 at Asp19 and this cleaved form (Δ19-RhoGDIβ) has been implicated in the apoptotic...
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| Gepubliceerd in: | Mol Med Rep |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
D.A. Spandidos
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5365007/ https://ncbi.nlm.nih.gov/pubmed/28260067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6199 |
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