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Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1

BACKGROUND AND AIMS: Hepatitis C virus (HCV)-induced chronic inflammation may induce oxidative stress which could compromise the repair of damaged DNA, rendering cells more susceptible to spontaneous or mutagen-induced alterations, the underlying cause of liver cirrhosis and hepatocellular carcinoma...

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Detalhes bibliográficos
Main Authors: Pal, Sampa, Polyak, Stephen J, Bano, Nazneen, Qiu, Wan Chong, Carithers, Robert L, Shuhart, Margaret, Gretch, David R, Das, Aditi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565844/
https://ncbi.nlm.nih.gov/pubmed/20074151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1746.2009.06128.x
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