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Perinuclear Mitochondrial Clustering Creates an Oxidant-Rich Nuclear Domain Required for Hypoxia-Induced Transcription

Mitochondria can govern local concentrations of second messengers, such as reactive oxygen species (ROS), and mitochondrial translocation to discrete subcellular regions may contribute to this signaling function. Here, we report that exposure of pulmonary artery endothelial cells to hypoxia triggere...

詳細記述

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書誌詳細
主要な著者: Al-Mehdi, Abu-Bakr, Pastukh, Viktor M., Swiger, Brad M., Reed, Darla J., Patel, Mita R., Bardwell, Gina C., Pastukh, Viktoriya V., Alexeyev, Mikhail F., Gillespie, Mark N.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565837/
https://ncbi.nlm.nih.gov/pubmed/22763339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002712
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