Structural insights into human heme oxygenase-1 inhibition by potent and selective azole-based compounds

The development of heme oxygenase (HO) inhibitors, especially those that are isozyme-selective, promises powerful pharmacological tools to elucidate the regulatory characteristics of the HO system. It is already known that HO has cytoprotective properties and may play a role in several disease state...

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Bibliographic Details
Main Authors: Rahman, Mona N., Vukomanovic, Dragic, Vlahakis, Jason Z., Szarek, Walter A., Nakatsu, Kanji, Jia, Zongchao
Format: Artigo
Language:Inglês
Published: The Royal Society 2013
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565801/
https://ncbi.nlm.nih.gov/pubmed/23097500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0697
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