Essential Role for Rac1 in Cocaine-Induced Structural Plasticity of Nucleus Accumbens Neurons

Repeated cocaine administration increases the dendritic arborization of nucleus accumbens neurons, but the underlying signaling events remain unknown. Here, we show that repeated cocaine negatively regulates the active form of Rac1, a small GTPase that controls actin remodeling in other systems. We...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Dietz, David M., Sun, Haosheng, Lobo, Mary Kay, Cahill, Michael E., Chadwick, Benjamin, Gao, Virginia, Koo, Ja Wook, Mazei-Robison, Michelle S., Dias, Caroline, Maze, Ian, Damez-Werno, Diane, Dietz, Karen C., Scobie, Kimberly N., Ferguson, Deveroux, Christoffel, Daniel, Ohnishi, Yoko, Hodes, Georgia E., Zheng, Yi, Neve, Rachael L., Hahn, Klaus M., Russo, Scott J., Nestler, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565539/
https://ncbi.nlm.nih.gov/pubmed/22522400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3094
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars