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DNA damage induces nucleoid compaction via the Mre11-Rad50 complex in the archaeon Haloferax volcanii
In prokaryotes the genome is organized in a dynamic structure called the nucleoid, which is embedded in the cytoplasm. We show here that in the archaeon Haloferax volcanii, compaction and reorganization of the nucleoid is induced by stresses that damage the genome or interfere with its replication....
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Blackwell Publishing Ltd
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565448/ https://ncbi.nlm.nih.gov/pubmed/23145964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12091 |
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