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DNA damage induces nucleoid compaction via the Mre11-Rad50 complex in the archaeon Haloferax volcanii

In prokaryotes the genome is organized in a dynamic structure called the nucleoid, which is embedded in the cytoplasm. We show here that in the archaeon Haloferax volcanii, compaction and reorganization of the nucleoid is induced by stresses that damage the genome or interfere with its replication....

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Detalhes bibliográficos
Main Authors: Delmas, Stéphane, Duggin, Iain G, Allers, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565448/
https://ncbi.nlm.nih.gov/pubmed/23145964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12091
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