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Kinetic Studies of Inhibition of the Aβ(1–42) Aggregation Using a Ferrocene-tagged β-Sheet Breaker Peptide

The aggregation of amyloidogenic proteins/peptides has been closely linked to the neuropathology of several important neurological disorders. In Alzheimer's disease (AD), amyloid beta (Aβ) peptides and their aggregation are believed to be at least partially responsible for the etiology of AD. T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Lin, Yagnik, Gargey, Peng, Yong, Wang, Jianxiu, Xu, H. Howard, Hao, Yuanqiang, Liu, You-Nian, Zhou, Feimeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565064/
https://ncbi.nlm.nih.gov/pubmed/23232068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.11.025
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