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Type I IFN response and innate immune sensing of cancer

Unexpectedly, many cancers appear to induce a spontaneous adaptive T cell response. The presence of a T cell infiltrate has been linked to favorable clinical outcome in multiple cancer types. However, the innate immune pathways that bridge to an adaptive immune response under sterile conditions are...

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Detalhes bibliográficos
Main Authors: Fuertes, Mercedes B., Woo, Seng-Ryong, Burnett, Byron, Fu, Yang-Xin, Gajewski, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565059/
https://ncbi.nlm.nih.gov/pubmed/23122052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.10.004
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