Type I IFN Receptor Regulates Neutrophil Functions and Innate Immunity to Leishmania Parasites

Type I IFNs exert diverse effector and regulatory functions in host immunity to viral and nonviral infections; however, the role of endogenous type I IFNs in leishmaniasis is unclear. We found that type I IFNR-deficient (IFNAR(−/−)) mice developed attenuated lesions and reduced Ag-specific immune re...

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Библиографические подробности
Главные авторы: Xin, Lijun, Vargas-Inchaustegui, Diego A., Raimer, Sharon S., Kelly, Brent C., Hu, Jiping, Zhu, Leiyi, Sun, Jiaren, Soong, Lynn
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159077/
https://ncbi.nlm.nih.gov/pubmed/20483775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903273
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