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Type I IFN Receptor Regulates Neutrophil Functions and Innate Immunity to Leishmania Parasites
Type I IFNs exert diverse effector and regulatory functions in host immunity to viral and nonviral infections; however, the role of endogenous type I IFNs in leishmaniasis is unclear. We found that type I IFNR-deficient (IFNAR(−/−)) mice developed attenuated lesions and reduced Ag-specific immune re...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159077/ https://ncbi.nlm.nih.gov/pubmed/20483775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903273 |
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