A Pseudo-Atomic Model of the COPII Cage Obtained from CryoEM and Mass Spectrometry Analyses

COPII vesicles transport proteins from the ER to the Golgi apparatus. Previous cryoEM structures of the COPII cage lacked the resolution necessary to determine the residues of Sec13 and Sec31 that mediate assembly and flexibility of the COPII cage. Here we present a 12Å-resolution structure of the C...

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Main Authors: Noble, Alex J., Zhang, Qian, O’Donnell, Jason, Hariri, Hanaa, Bhattacharya, Nilakshee, Marshall, Alan G., Stagg, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565055/
https://ncbi.nlm.nih.gov/pubmed/23262493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2467
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