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A Pseudo-Atomic Model of the COPII Cage Obtained from CryoEM and Mass Spectrometry Analyses

COPII vesicles transport proteins from the ER to the Golgi apparatus. Previous cryoEM structures of the COPII cage lacked the resolution necessary to determine the residues of Sec13 and Sec31 that mediate assembly and flexibility of the COPII cage. Here we present a 12Å-resolution structure of the C...

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Détails bibliographiques
Auteurs principaux: Noble, Alex J., Zhang, Qian, O’Donnell, Jason, Hariri, Hanaa, Bhattacharya, Nilakshee, Marshall, Alan G., Stagg, Scott M.
Format: Artigo
Langue:Inglês
Publié: 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565055/
https://ncbi.nlm.nih.gov/pubmed/23262493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2467
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