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Insights into the Mechanisms of Membrane Curvature and Vesicle Scission by the Small GTPase Sar1 in the Early Secretory Pathway

The small GTPase protein Sar1 is known to be involved in both the initiation of COPII coated vesicle formation and scission of the nascent vesicle from the ER. The molecular details for the mechanism of membrane remodeling by Sar1 remain unresolved. Here we show that Sar1 transforms synthetic liposo...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Hariri, Hanaa, Bhattacharya, Nilakshee, Johnson, Kerri, Noble, Alex J, Stagg, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254083/
https://ncbi.nlm.nih.gov/pubmed/25193674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.08.023
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