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Jelly Belly Trans-Synaptic Signaling to Anaplastic Lymphoma Kinase Regulates Neurotransmission Strength and Synapse Architecture

In Drosophila the secreted signaling molecule Jelly Belly (Jeb) activates Anaplastic Lymphoma Kinase (Alk), a receptor tyrosine kinase, in multiple developmental and adult contexts. We have shown previously that Jeb and Alk are highly enriched at Drosophila synapses within the CNS neuropil and neuro...

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Detalles Bibliográficos
Main Authors: Rohrbough, Jeffrey, Kent, Karla S., Broadie, Kendal, Weiss, Joseph B.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565053/
https://ncbi.nlm.nih.gov/pubmed/22949158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22056
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