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Secreted tissue inhibitor of matrix metalloproteinase restricts trans-synaptic signaling to coordinate synaptogenesis

Synaptogenesis is coordinated by trans-synaptic signals that traverse the specialized synaptomatrix between presynaptic and postsynaptic cells. Matrix metalloproteinase (Mmp) activity sculpts this environment, balanced by secreted tissue inhibitors of Mmp (Timp). Here, we use the simplified Drosophi...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Shilts, Jarrod, Broadie, Kendal
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536919/
https://ncbi.nlm.nih.gov/pubmed/28576972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.200808
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