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Nuclear Receptor Corepressors are Required for the Histone Deacetylase Activity of HDAC3 In Vivo

Histone deacetylase 3 (HDAC3) is an epigenome-modifying enzyme that is required for normal mouse development and tissue-specific functions. In vitro, HDAC3 protein itself has minimal enzyme activity, but gains its histone deacetylation function from stable association with the conserved deacetylase...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: You, Seo-Hee, Lim, Hee-Woong, Sun, Zheng, Broache, Molly, Won, Kyoung-Jae, Lazar, Mitchell A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565028/
https://ncbi.nlm.nih.gov/pubmed/23292142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2476
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