Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

Several novel anti-CD20 monoclonal antibodies are currently in development with the aim of improving the treatment of B cell malignancies. Mutagenesis and epitope mapping studies have revealed differences between the CD20 epitopes recognized by these antibodies. Recently, X-ray crystallography studi...

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Detaylı Bibliyografya
Asıl Yazarlar: Klein, Christian, Lammens, Alfred, Schäfer, Wolfgang, Georges, Guy, Schwaiger, Manfred, Mössner, Ekkehard, Hopfner, Karl-Peter, Umaña, Pablo, Niederfellner, Gerhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564883/
https://ncbi.nlm.nih.gov/pubmed/23211638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.22771
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