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Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties
Several novel anti-CD20 monoclonal antibodies are currently in development with the aim of improving the treatment of B cell malignancies. Mutagenesis and epitope mapping studies have revealed differences between the CD20 epitopes recognized by these antibodies. Recently, X-ray crystallography studi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564883/ https://ncbi.nlm.nih.gov/pubmed/23211638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.22771 |
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