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Mapping epitopes for 20 monoclonal antibodies to CR1

Complement receptor type one (CR1; CD35) binds and processes C3b and C4b opsonized immune complexes and regulates complement activation. We have characterized the epitopes of 13 previously reported and seven new MoAbs to human CR1. The MoAbs formed seven groups based on their reactivity with a panel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nickells, M, Hauhart, R, Krych, M, Bala Subramanian, V, Geoghegan-Barek, K, Marsh, H C, Atkinson, J P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904933/
https://ncbi.nlm.nih.gov/pubmed/9566786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00549.x
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