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Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis
Mice lacking Junctional Adhesion Molecule A (JAM-A, encoded by F11r) exhibit enhanced intestinal epithelial permeability, bacterial translocation, and elevated colonic lymphocyte numbers, yet do not develop colitis. To investigate the contribution of adaptive immune compensation in response to incre...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564580/ https://ncbi.nlm.nih.gov/pubmed/22981539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.017 |
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