Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis

Mice lacking Junctional Adhesion Molecule A (JAM-A, encoded by F11r) exhibit enhanced intestinal epithelial permeability, bacterial translocation, and elevated colonic lymphocyte numbers, yet do not develop colitis. To investigate the contribution of adaptive immune compensation in response to incre...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Khounlotham, Manirath, Kim, Wooki, Peatman, Eric, Nava, Porfirio, Medina-Contreras, Oscar, Addis, Caroline, Koch, Stefan, Fournier, Benedicte, Nusrat, Asma, Denning, Timothy L., Parkos, Charles A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564580/
https://ncbi.nlm.nih.gov/pubmed/22981539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.017
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk