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The Wnt Antagonist Dkk1 Regulates Intestinal Epithelial Homeostasis and Wound Repair
BACKGROUND & AIMS: Dkk1 is a secreted antagonist of the Wnt/β-catenin signaling pathway. It is induced by inflammatory cytokines during colitis and exacerbates tissue damage by promoting apoptosis of epithelial cells. However, little is known about the physiologic role of Dkk1 in normal intestin...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3551610/ https://ncbi.nlm.nih.gov/pubmed/21440550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.03.043 |
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