Interferon-γ regulates intestinal epithelial homeostasis through converging β-catenin signaling pathways

Inflammatory cytokines have been proposed to regulate epithelial homeostasis during intestinal inflammation. We report here that interferon-γ (IFN-γ) regulates the crucial homeostatic functions of cell proliferation and apoptosis through serine-threonine protein kinase AKT-β-catenin and Wingless-Int...

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Hauptverfasser: Nava, Porfirio, Koch, Stefan, Laukoetter, Mike G, Lee, Winston Y, Kolegraff, Keli, Capaldo, Christopher T, Beeman, Neal, Addis, Caroline, Gerner-Smidt, Kirsten, Neumaier, Irmgard, Skerra, Arne, Li, Linheng, Parkos, Charles A, Nusrat, Asma
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859189/
https://ncbi.nlm.nih.gov/pubmed/20303298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.03.001
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